There are a lot of topics that D&D isn’t ready-made to explore. As best as I can tell, disease (chronic or acute) is one of them.
This line of thought came up for me while talking with my sib about dangerous encounters in a weird fantasy / sci-fi / horror adventure campaign I’m running for some friends. It’s a roughly post-apocalyptic setting, based in The Hub, in which the apocalypse(s) in question took place a variable amount of time ago and in different fashions, depending on where the PCs explore. Some of the perils the PCs face include radiological disasters, and radioactive environments or threats.
My sib, naturally, asked what I’d done on the topic of cancer.
I had some grim thoughts about the future of our civilization today, and turned them into a fantastical exploration of alternate worlds… because that’s how my brain works, I guess. Join my escapade, and learn a little bit about Rare Earth Elements, modern technology, and climate change while you’re at it.